4.5 Article

Fluorescent sodium ion indicators based on the 1,7-diaza-15-crown-5 system

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 14, Issue 21, Pages 5313-5316

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2004.08.022

Keywords

fluoroionophore; metal ion indicator; chelator

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A series of novel sodium ion-sensitive fluorescent reagents suitable for biological applications is described. The chelator nitrogen atom substituents affect the selectivity and affinity of cation binding, while the nature of the fluorophore determines the type of fluorescent response to metal ion chelation. (C) 2004 Elsevier Ltd. All rights reserved.

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