Journal
INFECTION AND IMMUNITY
Volume 72, Issue 11, Pages 6733-6737Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.72.11.6733-6737.2004
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Funding
- NIAID NIH HHS [R37 AI014764, AI4764, R01 AI014764] Funding Source: Medline
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Superantigen peptide antagonists failed to block T-cell activation and cytokine production as well as toxic shock induced by staphylococcal enterotoxin B (SEB) in HLA class II transgenic mice. They also failed to inhibit the binding of SEB to HLA class II molecules as well as activation of human T lymphocytes in vitro.
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