Journal
PEDIATRIC NEPHROLOGY
Volume 19, Issue 11, Pages 1278-1280Publisher
SPRINGER
DOI: 10.1007/s00467-004-1566-1
Keywords
cystatin C; glomerular filtration rate; nephrotic syndrome
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The aim of this study was to evaluate changes in urine and plasma concentrations of cystatin C in children with a relapse of the idiopathic nephrotic syndrome (INS). The study group comprised 12 children with INS with proteinuria and 12 children in an 8-week remission, both treated with steroids. Twelve healthy children served as controls. Cystatin C was detectable in the urine of children with proteinuria. The study suggests that massive proteinuria may influence renal cystatin C handling.
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