Journal
NATURE REVIEWS MICROBIOLOGY
Volume 2, Issue 11, Pages 861-871Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro1025
Keywords
-
Categories
Ask authors/readers for more resources
There is little doubt that the main component of the transmissible agent of spongiform encephalopathies - the prion - is a conformational variant of the ubiquitous host protein PrPC, and that the differing properties of various prion strains are associated with different abnormal conformations of this protein. The precise structure of the prion is not yet known, nor are the mechanisms of infection, conformational conversion and pathogenesis understood.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available