Journal
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Volume 123, Issue 5, Pages 924-929Publisher
ELSEVIER SCIENCE INC
DOI: 10.1111/j.0022-202X.2004.23475.x
Keywords
kit; laser ablation; melanocyte; regeneration; zebrafish
Categories
Funding
- NIGMS NIH HHS [R01-GM 56988] Funding Source: Medline
Ask authors/readers for more resources
A method to specifically ablate melanocytes in a genetically tractable organism would facilitate the analysis of melanocyte regeneration and regulation. We have demonstrated that a Q-switched neodymium:yttrium-aluminum-garnet dermatology laser kills larval melanocytes in zebrafish. Following melanocyte ablation, new melanocytes regenerate from unpigmented precursors. We show that melanocyte regeneration following laser ablation requires kit receptor tyrosine kinase.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available