4.4 Article

Left inferior prefrontal cortex activity reflects inhibitory rather than facilitatory priming

Journal

JOURNAL OF COGNITIVE NEUROSCIENCE
Volume 16, Issue 9, Pages 1552-1561

Publisher

MIT PRESS
DOI: 10.1162/0898929042568523

Keywords

-

Funding

  1. Wellcome Trust [075481] Funding Source: Medline

Ask authors/readers for more resources

Functional neuroimaging has demonstrated reduced activation correlated with behavioral priming effects, a finding generally interpreted in terms of facilitated retrieval of target items in the context of related primes. Without a neutral prime, however, one cannot separate facilitatory effects of related primes from inhibitory effects of unrelated primes. Here we report an auditory semantic priming paradigm with congruent (The boy bounced the BALL''), neutral (The next item is BALL''), and incongruent (Pasta is my favorite kind of BALL'') sentence trials. As previously reported, reduced left inferior prefrontal cortex activation was observed for congruent relative to incongruent trials; however, the neutral condition allowed us to show that the effect arose from increased activation in the incongruent condition rather than reduced activation for congruent trials. Our results suggest that the left inferior prefrontal cortex inhibits interference from prepotent representations in order to select a task-appropriate target, and is consistent with its broader role in behavioral inhibition.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available