Journal
ADVANCED MATERIALS
Volume 16, Issue 21, Pages 1917-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200400014
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- NIDCR NIH HHS [T32 DE007057] Funding Source: Medline
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The degradation rates of hydrogels are shown to be regulated by the modulation of the dissociation rates of the polymer chains via a size mismatch in the crosslinking zones. This method (used to control degradation) can be exploited in order to engineer cartilage tissue in vivo (see Figure).
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