4.3 Article

Practical synthesis of optically active fluorine-substituted α-phenylethylamines by retardation of hydrogenolytic cleavage at benzylic position

Journal

CHEMISTRY LETTERS
Volume 33, Issue 11, Pages 1424-1425

Publisher

CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2004.1424

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High regioselectivity in hydrogenolysis of bis(alpha-methylbenzyl)amines having a fluorine atom on aromatic ring results from retardation of hydrogenolytic cleavage at benzylic position of fluorine-substituted aromatic ring.

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