Journal
SCIENCE
Volume 306, Issue 5699, Pages 1172-1174Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1102036
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We assess the phylogenetic potential of similar to300,000 protein sequences sampled from Swiss-Prot and GenBank. Although only a small subset of these data was potentially phylogenetically informative, this subset retained a substantial fraction of the original taxonomic diversity. Sampling biases in the databases necessitate building phylogenetic data sets that have large numbers of missing entries. However, an analysis of two supermatrices suggests that even data sets with as much as 92% missing data can provide insights into broad sections of the tree of life.
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