Journal
TETRAHEDRON LETTERS
Volume 45, Issue 47, Pages 8733-8736Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.09.131
Keywords
sonogashira reaction; palladium; water; aryl halides; alkynylation
Categories
Ask authors/readers for more resources
The palladium catalyzed alkynylation of aryl halides (Sonogashira reaction) has been achieved in pure water without any additives or phase transfer catalysts. The reaction, which requires only 0.5 mol% of Pd(PPh3)(4) catalyst, is remarkably fast (30 min at 70degreesC) producing high yields of the aryl alkyne products. (C) 2004 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
