Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 101, Issue 46, Pages 16216-16221Publisher
NATL ACAD SCIENCES
DOI: 10.1073/pnas.0407188101
Keywords
embryonic nervous system; neural mutants; neural development
Categories
Ask authors/readers for more resources
RNA interference was used to screen 3,314 Drosophila double-stranded RNAs, corresponding to approximate to25% of Drosophila genes, for genes that affect the development of the embryonic nervous system. RNA-interference-mediated gene silencing in Drosophila embryos resulted in loss-of-function mutant phenotypes for 43 genes, which is 1.3% of the genes that were screened. We found 18 genes that were not known previously to affect the development of the nervous system. The functions of some of the genes are unknown. Other genes encode protein kinases, transcription factors, and signaling proteins, as well as proteins with other functions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available