Journal
APPLIED PHYSICS LETTERS
Volume 95, Issue 20, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.3250432
Keywords
drops; emulsions; fractionation; hydrodynamics; microfluidics
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Funding
- Ministere de l'Enseignement Superieur et de la Recherche, Centre National de la Recherche Scientifique (CNRS), Agence National de la Recherche (ANR) [ANR-05-BLAN0397]
- Human Frontier Science Program (HFSP)
- Fondation d'Entreprise EADS
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We describe a microfluidic system allowing fast and efficient size-dependent separation of droplets using hydrodynamics. This system allows efficient fractionation of droplets with a difference in volume as small as 2.33-fold (corresponding to a 1.33-fold difference in diameter of spherical droplets) at >4.5 kHz frequencies. To demonstrate the utility of the system we combined the size-fractionation module with a passive droplet fusion module to create an integrated microfluidic platform allowing the preparation of highly monodisperse emulsions composed of >99% pairwise fused droplets. This type of microfluidic platform should be useful for many droplet-based lab-on-a-chip applications.
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