Journal
APPLIED PHYSICS LETTERS
Volume 94, Issue 6, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.3080662
Keywords
biomedical measurement; chemical sensors; DNA; fluorescence; gold; molecular biophysics; nanobiotechnology; nanoparticles; optical sensors; quantum dots; radiation quenching; surface energy; surface plasmon resonance
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Funding
- Zhejiang University
- Swedish Foundation
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Gold nanorods (GNRs) with different localized surface plasmon resonance (LSPR) peaks and different thicknesses of polymer-coating were synthesized to validate that the distinct GNR-based quenching process of quantum dot (QD) emission follows the metal surface energy transfer theory. The quenching efficiency is directly related to the spectral overlap of GNR-LSPR absorption and QD-emission, as well as the separation distance between the two nanoparticles. GNRs are advantageous for DNA conjugation, and the high efficiency of GNR-QD quenching system was utilized for sensitive DNA detection.
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