4.6 Article

Conformational characteristics of β-glucan in laminarin probed by terahertz spectroscopy

Journal

APPLIED PHYSICS LETTERS
Volume 94, Issue 11, Pages -

Publisher

AMER INST PHYSICS
DOI: 10.1063/1.3100778

Keywords

bioelectric phenomena; biological techniques; bio-optics; molecular biophysics; molecular configurations; organic compounds; permittivity; refractive index; terahertz spectroscopy

Funding

  1. University of Seoul through the Academic Research [2007-0427-1024]
  2. Korea Institute of Industrial Technology(KITECH) [2004-가-12호] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  3. National Research Foundation of Korea [핵06A3102, 핵06A2807] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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We measured the binding-state-dependent power absorptions, refractive indices, and dielectric constants of triple-stranded helices (TSHs) and single-stranded helices (SSHs) beta-glucans in laminarin using terahertz time-domain spectroscopy (TDS). The SSH beta-glucan was obtained from a TSH beta-glucan laminarin by a chemical treatment with NaOH solution. The power absorption of TSH beta-glucan increased more rapidly than that of the SSH beta-glucan with the frequency increment. The refractive index and dielectric constants of TSH beta-glucan were also larger than those of the SSH beta-glucan. This result implies that terahertz-TDS is a very effective method in classifying the conformational state of beta-glucans.

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