Journal
FITOTERAPIA
Volume 75, Issue 7-8, Pages 801-804Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2004.05.002
Keywords
Thymus capitatus; T. vulgaris; T. serpyllum; Satureja hortensis; S. montana; Origanum dictamus; O. majorana; carvacrol
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Carvacrol is a component of numerous aromatic plants. Up to now, no toxicological data were available. Carvacrol show a weak activity in the mutagenicity studies. Moreover, in the metabolism study, carvacrol has shown to be excreted with urine after 24 h in large quantities or unchanged or as glucoronide and sulphate conjugates. The available data do not allow the assessment of the NOEL. Further toxicological studies are needed. (C) 2004 Elsevier B.V. All rights reserved.
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