Journal
APPLIED PHYSICS LETTERS
Volume 95, Issue 8, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.3194138
Keywords
cellular biophysics; elemental semiconductors; nanowires; silicon; transistors
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Funding
- German Research Foundation [OF22/7-1]
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Silicon nanowire (NW) transistors were fabricated in a top-down process. These devices were used to record the extracellular potential of the spontaneous activity of cardiac muscle HL-1 cells. Their signals were measured by direct dc sampling of the drain current. An improved signal-to-noise ratio compared to planar field-effect devices was observed. Furthermore the signal shape was evaluated and could be associated to different membrane currents. With these experiments, a qualitative description of the properties of the cell-NW contact was obtained and the suitability of these sensors for electrophysiological measurements in vitro was demonstrated.
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