Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 346, Issue 13-15, Pages 1661-1664Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200404182
Keywords
benzoxazoles; C-N and C-O cross-coupling; copper; cyclization; domino reactions; heterocycles
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Benzoxazoles can be efficiently prepared in a single step and in good yield from primary amides and o-dihalobenzenes using Cu catalysis. Starting from substituted o-bromochlorobenzenes this unusual domino reaction allows the regioselective formation of benzoxazoles.
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