Journal
MECHANISMS OF AGEING AND DEVELOPMENT
Volume 125, Issue 12, Pages 911-915Publisher
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/j.mad.2004.09.004
Keywords
ageing; gut; stem cells
Categories
Funding
- Biotechnology and Biological Sciences Research Council [BEP17042] Funding Source: Medline
- Biotechnology and Biological Sciences Research Council [BEP17042] Funding Source: researchfish
Ask authors/readers for more resources
The maintenance of integrity of gut epithelium is essential for the well being of the organism throughout life. Gut epithelium is maintained through a carefully controlled balance between cell loss and renewal, which is sustained by the proliferation of the epithelial stem cells. Although these stem cells show no intrinsic limit to their proliferative capacity, recent evidence indicates that they suffer important functional impairments during the course of ageing. This paper reviews what is currently known about intrinsic ageing of gut epithelial stem cells and its functional consequences. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
