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Meiosis: Cell-cycle controls shuffle and deal

Journal

NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 5, Issue 12, Pages 983-997

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nrm1526

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Funding

  1. NIGMS NIH HHS [R01 GM062207] Funding Source: Medline

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Meiosis is the type of cell division that gives rise to eggs and sperm. Errors in the execution of this process can result in the generation of aneuploid gametes, which are associated with birth defects and infertility in humans. Here, we review recent findings on how cell-cycle controls ensure the coordination of meiotic events, with a particular focus on the segregation of chromosomes.

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