4.6 Article

Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites

Journal

JOURNAL OF BONE AND MINERAL RESEARCH
Volume 19, Issue 12, Pages 1945-1954

Publisher

WILEY
DOI: 10.1359/JBMR.040916

Keywords

osteoporosis; aging; menopause; bone densitometry; bone QCT; BMD; bone geometry

Funding

  1. NCRR NIH HHS [M01 RR00585] Funding Source: Medline
  2. NIAMS NIH HHS [AR-27065] Funding Source: Medline

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In a population-based, cross-sectional study, we assessed age- and sex-specific changes in bone structure by QCT. Over life, the cross-sectional area of the vertebrae and proximal femur increased by similar to15% in both sexes, whereas vBMD at these sites decreased by 39-55% and 34-46%, respectively, with greater decreases in women than in men.

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