Journal
JOURNAL OF GENERAL VIROLOGY
Volume 85, Issue -, Pages 3647-3652Publisher
MICROBIOLOGY SOC
DOI: 10.1099/vir.0.80238-0
Keywords
-
Categories
Ask authors/readers for more resources
The genus Pestivirus within the family Flaviviridae currently consists of four different main species: Classical swine fever virus, Bovine viral diarrhea virus types 1 and 2 and Border disease virus. A fifth tentative species is represented by an isolate from a giraffe. In this study, a completely new pestivirus, isolated from a batch of fetal calf serum that was collected in Brazil, is described. It is proposed that the isolate D32/00_'HoBi' may constitute a novel sixth pestivirus species, because it is genetically, as well as antigenically, markedly different from all other pestiviruses. Based on the entire N-pro- and E2-encoding sequences, identities of <70% to all other pestivirus species were determined. Similarly, cross-neutralization and binding studies using antisera and mAbs revealed marked antigenic differences between D32/00 'HoBi' and all other pestiviruses.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available