Journal
INFECTION AND IMMUNITY
Volume 72, Issue 12, Pages 7311-7314Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.72.12.7311-7314.2004
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The expression of a beta-defensin, the lingual antimicrobial peptide (LAP), in response to mastitis was investigated by real-time PCR of RNA from mastitic and control udder quarters. There was a positive relationship between somatic cell count in milk and LAP expression. In situ hybridization showed that LAP mRNA was expressed in epithelial cells of mastitic tissue. These results suggest that LAP plays a role in the innate immune response to mastitis.
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