Journal
CHEMISTRY & BIOLOGY
Volume 11, Issue 12, Pages 1607-1617Publisher
CELL PRESS
DOI: 10.1016/j.chembiol.2003.08.012
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Funding
- NCI NIH HHS [CA42056, CA41986] Funding Source: Medline
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Biologically active, therapeutically useful, DNA binding natural products continue to reveal new paradigms for sequence-selective recognition, to enlist beautiful mechanisms of in situ activation for DNA modification, to define new therapeutic targets, to exploit new mechanisms to achieve cellular selectivity, and to provide a rich source of new drugs. These attributes arise in compact structures of complex integrated function.
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