Journal
ORGANIC LETTERS
Volume 6, Issue 25, Pages 4735-4738Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol048013v
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The synthesis and self-assembling properties of 8-aryl-2'-deoxyguanosine derivatives are described. Our studies suggest that a properly placed acetyl group can increase the stability and specificity of the resulting G-quadruplex supramolecules by enhancing noncovalent interactions such as hydrogen bonds and z-stacking.
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