Journal
MOLECULAR CELL
Volume 16, Issue 6, Pages 849-859Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2004.12.001
Keywords
-
Categories
Funding
- NCI NIH HHS [R01 CA 30488] Funding Source: Medline
Ask authors/readers for more resources
A number of cellular genes have recently been identified that actively inhibit retrovirus replication and so protect cells from infection. The genes target many distinct steps in the viral life cycle: entry, viral DNA synthesis, intracellular movement of viral nucleic acids, and viral gene expression. These restriction systems constitute newly appreciated components of an innate immunity that may be important for survival of a host exposed to retrovirus infection. It may someday be possible to enhance or activate these systems to induce antiviral states.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available