A highly efficient and recyclable silica-based scandium(III) interphase catalyst for cyanosilylation of carbonyl compounds

A new silica-based scandium(III) interphase catalyst 2 efficiently catalyzes the cyanosilylation of a variety of aldehydes and ketones. The catalyst shows high thermal stability (up to 300degreesC) and also is stable in both organic and polar solvents. It also could be recovered and reused for at least 10 reaction cycles without considerable loss of reactivity.