Journal
TETRAHEDRON LETTERS
Volume 46, Issue 1, Pages 69-74Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.11.046
Keywords
alkynylation; N-tosylimines; aryl acetylenes; ZnBr2; DIEA
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We found a suitable condition for the effective alkynylation of N-tosylimines with aryl acetylenes. The reaction tosylimines and aryl acetylenes in the presence of ZnBr2, and DIEA (N,N -diisopropylethylamine) in CH3CN afforded the desired N-tosyl propargylamines in moderate to good yields. (C) 2004 Elsevier Ltd. All rights reserved.
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