Journal
JOURNAL OF THE NEUROLOGICAL SCIENCES
Volume 228, Issue 1, Pages 3-5Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jns.2004.08.015
Keywords
demyelination; thyroiditis; autoimmune; encephalopathy; steroid-responsive
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Steroid responsive encephalopathy associated with autoimmune thyroiditis is a well-recognized complication of autoimmune thyroid disease. However, the characterization of the histopathological features of steroid responsive encephalopathy associated with autoimmune thyroiditis are limited to six cases. Reported pathological features include vasculitis involving venules and arterioles, lymphocytic perivascular cuffs and microglial activation. We report a case of SREAT with biopsy proven (on two occasions) primary CNS demyelination and radiological evidence of steroid responsiveness, identifying primary CNS demyelination as a complilation of autoimmune thyroid disease. (C) 2004 Elsevier B.V. All rights reserved.
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