4.2 Article

Nickel(II) chloride catalyzed one-pot synthesis of α-aminonitriles

Journal

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
Volume 225, Issue 2, Pages 169-171

Publisher

ELSEVIER
DOI: 10.1016/j.molcata.2004.09.005

Keywords

aldehydes; amines; trimethylsilyl cyanide; alpha-aminonitriles; nickel(II) chloride

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A simple and efficient method has been developed for the synthesis of alpha-aminonitrilesby simply mixing aldehydes, amines, and trimethylsilyl cyanides in the presence of a catalytic amount of NiCl2 at room temperature. (C) 2004 Elsevier B.V. All rights reserved.

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