4.0 Article

Glyco-quantum dots:: a new luminescent system with multivalent carbohydrate display

Journal

TETRAHEDRON-ASYMMETRY
Volume 16, Issue 2, Pages 387-391

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2004.12.002

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Nanoclusters of cadmium sulfide covalently bound to biologically significant neoglycoconjugates (glyco-QDs) have been synthesized by means of a single step solution procedure. The neoglycoconjugates confer the QDs water solubility, stability, and biological activity. The nanometer-sized glyco-QDs have been characterized by TEM, EDAX, H-1 NMR, UV-vis, and fluorescence spectroscopy. The carbohydrate conjugate nanocrystals can be used as bioactive fluorescence probes for specifically labeling carbohydrate cell receptors. (C) 2004 Elsevier Ltd. All rights reserved.

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