4.7 Article

3.0-tesla MR angiography of intracranial aneurysms: Comparison of time-of-flight and contrast-enhanced techniques

Journal

JOURNAL OF MAGNETIC RESONANCE IMAGING
Volume 21, Issue 2, Pages 97-102

Publisher

WILEY
DOI: 10.1002/jmri.20247

Keywords

contrast-enhanced magnetic resonance angiography; intracranial aneurysm; magnetic resonance angiography; time-of-flight magnetic resonance angiography; 3T and/or high field

Funding

  1. NCI NIH HHS [CA 37993-16] Funding Source: Medline

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Purpose: To determine whether 3.0-T elliptical-centric contrast-enhanced (CE) magnetic resonance (MR) angiography is superior to 3.0-T elliptical-centric time-of-flight (TOF) MR angiography in the detection and characterization of intracranial aneurysms, and to determine whether increasing the acquisition matrix size in 3.0-T CE MR angiography improves image quality. Materials and Methods: A total of 50 consecutive patients referred for MR angiographic evaluation of a known or suspected intracranial aneurysm underwent MR angiography. including three-dimensional TOF and elliptical-centric CE techniques at 3.0 T. The 3.0-T three-dimensional TOF and 3.0-T CE examinations were graded for image quality. A blind review identified the presence and location of aneurysms. Results: A total of 28 aneurysms were identified in 23 of the 50 patients. The 3.0-T TOF MR angiography had a higher mean score for image quality than the 3.0-T elliptical-centric CE MR angiography (P < 0.0001). A total of 14 patients with aneurysms had conventional angiography for comparison. The 3.0-T TOF showed all the aneurysms. whereas 3.0-T CE MR angiography did not show 1 of 19 aneurysms when conventional angiography was the reference standard. Conclusion: For imaging intracranial aneurysms. 3.0-T TOF MR angiography offers better image quality than 3.0-T CE MR angiography using the elliptical-centric technique.

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