Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 9, Issue 1, Pages 14-19Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.cbpa.2004.12.006
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Funding
- NCI NIH HHS [R33 CA99191] Funding Source: Medline
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Protein microarrays present an innovative and versatile approach to study protein abundance and function at an unprecedented scale. Given the chemical and structural complexity of the proteome, the development of protein microarrays has been challenging. Despite these challenges there has been a marked increase in the use of protein microarrays to map interactions of proteins with various other molecules, and to identify potential disease biomarkers, especially in the area of cancer biology. In this review, we discuss some of the promising advances made in the development and use of protein microarrays.
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