Journal
PHARMACOLOGY & THERAPEUTICS
Volume 105, Issue 2, Pages 151-163Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.pharmthera.2004.10.003
Keywords
biomaterial; cell; heart; scaffold; tissue engineering; transplantation
Categories
Ask authors/readers for more resources
Unlike heart valves or blood vessels. heart muscle has no replacement alternatives. The most challenging goal in the field of cardiovascular tissue engineering is the creation/ regeneration of an engineered heart muscle. Recent advances in methods of stem cell isolation, culture in bioreactors. and the synthesis of bioactive materials promise to create engineered cardiac tissue ex vivo. At the same time. new approaches arc conceived that explore ways to induce tissue regeneration after injury. The purpose of our review is to describe the principles status, and challenges of myocardial tissue engineering with emphasize on the concept of in situ cardiac tissue engineering and regeneration. (C) 2004 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available