4.7 Article

In vitro host-cell susceptibility to Usutu virus

Journal

EMERGING INFECTIOUS DISEASES
Volume 11, Issue 2, Pages 298-301

Publisher

CENTERS DISEASE CONTROL
DOI: 10.3201/eid1102.041016

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We investigated the susceptibility to Usutu virus (Flavivirus) of 13 permanent cell lines, 3 primary cell cultures, and chicken embryos. Vero, PK-15, and goose embryo fibroblast cells developed cytopathic effects; however, viral multiplication was detected in all mammalian cell types by immunohistochemical tests. Chicken embryo fibroblast cells and chicken embryos were resistant.

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