4.6 Article

Drugs used to treat osteoporosis: The critical need for a uniform nomenclature based on their action on bone remodeling

Journal

JOURNAL OF BONE AND MINERAL RESEARCH
Volume 20, Issue 2, Pages 177-184

Publisher

AMER SOC BONE & MINERAL RES
DOI: 10.1359/JBMR.041114

Keywords

bone densitometry; bone histomorphometry; osteoblasts; osteoporosis; novel entities

Funding

  1. NIAMS NIH HHS [AR27065] Funding Source: Medline
  2. NIA NIH HHS [P01 AG004875, P01 AG13918] Funding Source: Medline

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There continues to be uncertainty about the classification of available drugs for treating osteoporosis. We find that grouping them into anti-catabolic and anabolic classes based on the mechanisms of their action on bone remodeling and fracture reduction removes ambiguities and provides a relatively straightforward classification.

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