4.7 Article

The biocide triclosan selects Stenotrophomonas maltophilia mutants that overproduce the SmeDEF multidrug efflux pump

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 49, Issue 2, Pages 781-782

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.49.2.781-782.2005

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The possibility that triclosan selects Stenotrophomonas maltophilia mutants overexpressing the multidrug resistance pump SmeDEF is analyzed. Five out of 12 triclosan-selected mutants were less susceptible to antibiotics than the wild-type strain and overproduced SmeDEF. Results are discussed in relation to current debates on the potential selection of antibiotic-resistant bacteria by household biocides.

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