4.6 Article

Theoretical approach to the destruction or sterilization of drugs in aqueous solution

Journal

RADIATION PHYSICS AND CHEMISTRY
Volume 72, Issue 2-3, Pages 363-365

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.radphyschem.2004.02.007

Keywords

radiation processing; radiosterilization decontamination drugs; wastewater; computer simulation

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Two novel applications in the radiation processing of aqueous solutions of drugs are the sterilization of injectable drugs and the decontamination of hospital wastewaters by ionizing radiation. The parameters influencing the destruction of the drug in aqueous solutions are studied with a computer simulation program. This theoretical approach has revealed that the dose rate is the most important parameter that can be easily varied in order to optimize the destruction or the protection of the drug. (C) 2004 Elsevier Ltd. All rights reserved.

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