Journal
JOURNAL OF ANTIBIOTICS
Volume 58, Issue 2, Pages 103-110Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2005.13
Keywords
structure elucidation; Micromonospora; angucyclinones; tetracenequione glycosides; saquayamycin Z; lumichromes
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A detailed screening of the secondary metabolite pattern from Micromonospora sp. strain Tu 6368 resulted in the isolation of ten compounds belonging to five different structural families. The structures of the novel compounds 1-(alpha-ribofuranosyl)-lumichrome (3), retymicin (7), galtamycin B (11) and saquayamycin Z (14) were assigned by spectroscopic methods and chemical transformations. This strain fits our hypothesis that the metabolite analysis of biosynthetically talented strains leads readily to novel compounds.
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