4.5 Article

Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp Tu 6368 -: II.: Structure elucidation

Journal

JOURNAL OF ANTIBIOTICS
Volume 58, Issue 2, Pages 103-110

Publisher

JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2005.13

Keywords

structure elucidation; Micromonospora; angucyclinones; tetracenequione glycosides; saquayamycin Z; lumichromes

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A detailed screening of the secondary metabolite pattern from Micromonospora sp. strain Tu 6368 resulted in the isolation of ten compounds belonging to five different structural families. The structures of the novel compounds 1-(alpha-ribofuranosyl)-lumichrome (3), retymicin (7), galtamycin B (11) and saquayamycin Z (14) were assigned by spectroscopic methods and chemical transformations. This strain fits our hypothesis that the metabolite analysis of biosynthetically talented strains leads readily to novel compounds.

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