Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 17, Issue 1, Pages 58-64Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2004.11.008
Keywords
-
Categories
Funding
- PHS HHS [41751, 29564, 45580] Funding Source: Medline
Ask authors/readers for more resources
Recent advances have shown the crucial role of histone-modifying enzymes in controlling gene activation and repression. This led to the 'histone code' hypothesis, which proposes that combinations of histone modifications work in concert to affect specific gene expression. Mounting evidence suggests that the class II transactivator modulates promoter accessibility by coordinating the recruitment of chromatin modifiers in a time-dependent fashion. MHC-II expression is exquisitely controlled by these highly specific, coordinated and dynamic interactions at the promoter.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available