Journal
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
Volume 78, Issue 2, Pages 307-315Publisher
CHEMICAL SOC JAPAN
DOI: 10.1246/bcsj.78.307
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NaBH4 in wet THF can readily reduce varieties of carbonyl compounds such as aldehydes, ketones, conjugated enones, acyloins, and alpha-diketones to their corresponding alcohols in good to excellent yields. Reduction reactions were performed at room temperature or under reflux condition. In addition, the chemoselective reduction of aldehydes over ketones was accomplished successfully with this reducing system.
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