Journal
EUROPEAN JOURNAL OF OPHTHALMOLOGY
Volume 15, Issue 2, Pages 228-232Publisher
WICHTIG EDITORE
DOI: 10.1177/112067210501500209
Keywords
brimonidine; bleeding complications; cataract surgery
Categories
Ask authors/readers for more resources
PURPOSE. To evaluate the effect of prophylactic brimonidine on bleeding complications after cataract surgery. METHODS. The authors performed a prospective, double-masked, two-surgeon study of 137 patients (137 eyes) who underwent phacoemulsification and intraocular lens implantation with or without prophylactic brimonidine before cataract surgery. The authors also compared the effect of brimonidine among patients with systemic diseases such as diabetes mellitus (types I and II), hypertension, and anticoagulant or antiplatelet treatment. RESULTS. Subconjunctival hemorrhage was observed in 73.70% of the patients not treated with brimonidine before surgery and in only 23.75% of the patients who were given prophylactic brimonidine (p < 0.001, chi(2)). The grade of hemorrhage was also statistically significant(p < 0.001, Mann-Whitney). No statistically significant difference with regard to the presence of hemorrhage in diabetic patients or in the anticoagulant or antiplatelet treatment group was observed. However, a statistically significant difference (p < 0.027, chi(2)) was found between hypertensive patients treated and not treated with prophylactic brimonidine before cataract surgery. CONCLUSIONS: This study suggests that brimonidine administered before cataract surgery may significantly reduce subconjunctival hemorrhage in the general population. It has been shown to be beneficial in hypertensive patients. A strong statistical trend, but not significance has been found in diabetic patients or in patients treated with antiplatelet or anticoagulant drugs, but further studies are needed to reach conclusive results.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available