Journal
APPLIED ORGANOMETALLIC CHEMISTRY
Volume 22, Issue 8, Pages 466-470Publisher
WILEY
DOI: 10.1002/aoc.1427
Keywords
NbCl5; catalysis; aldehydes; amines; trimethylsilyl cyanide; alpha-aminonitriles
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A simple and efficient one-pot method has been developed for the synthesis of alpha-aminonitriles by concurrent reaction of aldehydes, amines and trimethylsilyl cyanide with a catalytic amount of NbCl5 (10 mol%) in CH3CN at room temperature. Copyright (C) 2008 John Wiley & Sons, Ltd.
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