Journal
DRUG DISCOVERY TODAY
Volume 10, Issue 5, Pages 365-372Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1359-6446(05)03369-6
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This article discusses the most recent achievements in understanding the biological implications of the small-world and scale-free global topological properties of genetic, proteomic and metabolic networks. Most importantly, these networks are highly clustered and have small node-to-node distances. With their few very connected nodes, which are statistically unlikely to fail under random conditions, the proper functioning of these systems is maintained under external perturbations.
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