Journal
AMERICAN JOURNAL OF PSYCHIATRY
Volume 162, Issue 3, Pages 433-440Publisher
AMER PSYCHIATRIC PUBLISHING, INC
DOI: 10.1176/appi.ajp.162.3.433
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This article, which seeks to sketch a coherent conceptual and philosophical framework for psychiatry, confronts two major questions: how do mind and brain interrelate, and how can we integrate the multiple explanatory perspectives of psychiatric illness? Eight propositions are proposed and defended: 1) psychiatry is irrevocably grounded in mental, first-person experiences; 2) Cartesian substance dualism is false; 3) epiphenomenalism is false; 4) both brain -> mind and mind -> brain causality are real; 5) psychiatric disorders are etiologically complex, and no more spirochete-like discoveries will be made that explain their origins in simple terms; 6) explanatory pluralism is preferable to monistic explanatory approaches, especially biological reductionism; 7) psychiatry must move beyond a prescientific battle of paradigms to embrace complexity and support empirically rigorous and pluralistic explanatory models; 8) psychiatry should strive for patchy reductionism with the goal of piecemeal integration in trying to explain complex etiological pathways to illness bit by bit.
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