Journal
APPLIED OPTICS
Volume 52, Issue 1, Pages A97-A101Publisher
OPTICAL SOC AMER
DOI: 10.1364/AO.52.000A97
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Funding
- National Science Foundation [CBET 08-46660, CBET-1040462]
- National Cancer Institute [R21 CA147967-01]
- NATIONAL CANCER INSTITUTE [R21CA147967] Funding Source: NIH RePORTER
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In off-axis interferometry, we usually have to deal with the unwrapping process, which is very computationally intensive and prevents us from real time phase reconstruction. The wrapping problem usually occurs when imaging thick objects, which introduce phase shifts of more than 2 pi radians. However, in off-axis interferometry, the nonzero angle of interference of the two beams creates a ramp in the phase across the image that can produce phase wrapping errors. In this paper, we propose a simple technique that avoids the need for the unwrapping step in reconstructing quantitative phase images in white light diffraction phase microscopy of thin samples. We show that this approach can improve significantly the phase reconstruction speed and allow high impact applications, such as real-time blood testing. (C) 2012 Optical Society of America
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