Journal
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
Volume 47, Issue 3, Pages 226-234Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.jom.0000155711.88781.91
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Funding
- NCRR NIH HHS [M01 RR 00051] Funding Source: Medline
- NHLBI NIH HHS [N01 HR 56073, N01 HR 56075, N01 HR 56074, N01 HR 56069, N01 HR 56066, N01 HR 56071, N01 HR 56070, N01 HR 56065, N01 HR 56072, N01 HR 56067, N01 HR 56068] Funding Source: Medline
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Objective: To determine whether specific occupations and industries may he associated with sarcoidosis. Methods: A Case Control Etiologic Study of Sarcoidosis (ACCESS) obtained occupational and environmental histories on 706 newly diagnosed sarcoidosis cases and matched controls. We used Standard Industrial Classification (SIC) and Standard Occupational Classification (SOC) to assess occupational contributions to sarcoidosis risk. Results: Univariable analysis identified elevated risk of sarcoidosis for workers with industrial organic dust exposures, especially in Caucasian, workers. Workers for suppliers of building materials, hardware, and gardening materials were at an. increased risk of sarcoidosis as were educators. Work providing childcare was negatively associated with sarcoidosis risk.,jobs with metal dust or metal fume exposures were negatively associated with sarcoidosis risk, especially in Caucasian workers. Conclusions: In this study, we found duct exposures in particular occupational settings may contribute to sarcoidosis risk.
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