Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 69, Issue 3, Pages 628-630Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.69.628
Keywords
pentabromopseudilin; Alteromonas luteoviolaceus; biosynthesis; D,L-[5-C-13]proline
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The biosynthesis of the potent marine antibiotic, pentabromopseudilin (1), was investigated. Feeding studies with Alteromonas luteoviolaceus were performed on a defined medium. D,L-[5-C-13]proline was incorporated symmetrically, demonstrating that the pyrrole ring of pentabromopseudilin is derived from proline.
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