4.4 Article

Transcriptome of Treponema pallidum:: Gene expression profile during experimental rabbit infection

Journal

JOURNAL OF BACTERIOLOGY
Volume 187, Issue 5, Pages 1866-1874

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.187.5.1866-1874.2005

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Funding

  1. NEI NIH HHS [R01 EY013759] Funding Source: Medline
  2. NIAID NIH HHS [R01 AI049252, R01 AI49252, AI45842, R01 AI045842] Funding Source: Medline
  3. NIDA NIH HHS [R01 DA013759] Funding Source: Medline
  4. NIDCR NIH HHS [R01 DE13759, R01 DE12488] Funding Source: Medline

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RNA transcript levels in the syphilis spirochete Treponema pallidum subsp. pallidum (Nichols) isolated from experimentally infected rabbits were determined by the use of DNA microarray technology. This characterization of the T. pallidum transcriptome during experimental infection provides further insight into the importance of gene expression levels for the survival and pathogenesis of this bacterium.

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