Journal
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume 102, Issue 20, Pages 8629-8646Publisher
SPRINGER
DOI: 10.1007/s00253-018-9209-9
Keywords
Metagenomics; Human microbiome; Microbiology and clinical research; Next generation sequencing
Categories
Funding
- Wellcome Trust
- MRC
- National Institute for Health Research (NIHR)
- Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust
- King's College London
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Owing to the increased cost-effectiveness of high-throughput technologies, the number of studies focusing on the human microbiome and its connections to human health and disease has recently surged. However, best practices in microbiology and clinical research have yet to be clearly established. Here, we present an overview of the challenges and opportunities involved in conducting a metagenomic study, with a particular focus on data processing and analytical methods.
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