4.7 Article

Experimental bacteriophage protection against Staphylococcus aureus abscesses in a rabbit model

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 49, Issue 3, Pages 1220-1221

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.49.3.1220-1221.2005

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In a rabbit model of wound infection caused by Staphylococcus aureus, 2 x 10(9) PFU of staphylococcal phage prevented abscess formation in rabbits when it was injected simultaneously with S. aureus (8 x 10(7) CFU) into the same subcutaneous site. Phage multiplied in the tissues. Phages might be a valuable prophylaxis against staphylococcal infection.

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